BindingDB logo
myBDB logout

BDBM50247607 (1S,2S)-N1-hydroxy-N2-(4-((2-methylquinolin-4-yloxy)methyl)phenyl)cyclohexane-1,2-dicarboxamide::CHEMBL491084

SMILES: Cc1cc(OCc2ccc(NC(=O)[C@H]3CCCC[C@@H]3C(=O)NO)cc2)c2ccccc2n1

InChI Key: InChIKey=VMQGJUBJOLUGES-PMACEKPBSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50247607   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Disintegrin and metalloproteinase domain-containing protein 17


(Homo sapiens (Human))
BDBM50247607
PNG
((1S,2S)-N1-hydroxy-N2-(4-((2-methylquinolin-4-ylox...)
Show SMILES Cc1cc(OCc2ccc(NC(=O)[C@H]3CCCC[C@@H]3C(=O)NO)cc2)c2ccccc2n1
Show InChI InChI=1S/C25H27N3O4/c1-16-14-23(21-8-4-5-9-22(21)26-16)32-15-17-10-12-18(13-11-17)27-24(29)19-6-2-3-7-20(19)25(30)28-31/h4-5,8-14,19-20,31H,2-3,6-7,15H2,1H3,(H,27,29)(H,28,30)/t19-,20-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8n/an/an/an/an/an/a



The M. S. University of Baroda

Curated by ChEMBL


Assay Description
Inhibition of TACE


Bioorg Med Chem 17: 444-59 (2009)


Article DOI: 10.1016/j.bmc.2008.11.067
BindingDB Entry DOI: 10.7270/Q2WH2QWZ
More data for this
Ligand-Target Pair