BDBM50248167 2-(1,3-thiazol-4-yl)-1H-benzimidazole-5-sulfonamide::2-(thiazol-4-yl)-1H-benzo[d]imidazole-5-sulfonamide::CHEMBL455271

SMILES NS(=O)(=O)c1ccc2nc([nH]c2c1)-c1cscn1

InChI Key InChIKey=KGMVTZZDGKDTEU-UHFFFAOYSA-N

Data  12 KI

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50248167   

TargetCarbonic anhydrase 9(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50248167(2-(1,3-thiazol-4-yl)-1H-benzimidazole-5-sulfonamid...)
Affinity DataKi:  6.40nMAssay Description:Inhibition of human recombinant CA9 catalytic domain by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50248167(2-(1,3-thiazol-4-yl)-1H-benzimidazole-5-sulfonamid...)
Affinity DataKi:  17.8nMAssay Description:Inhibition of human recombinant CA12 catalytic domain by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50248167(2-(1,3-thiazol-4-yl)-1H-benzimidazole-5-sulfonamid...)
Affinity DataKi:  25nMAssay Description:Inhibition of human recombinant full length CA6 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50248167(2-(1,3-thiazol-4-yl)-1H-benzimidazole-5-sulfonamid...)
Affinity DataKi:  40.9nMAssay Description:Inhibition of human recombinant full length CA5B by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50248167(2-(1,3-thiazol-4-yl)-1H-benzimidazole-5-sulfonamid...)
Affinity DataKi:  48.9nMAssay Description:Inhibition of human recombinant full length CA4 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50248167(2-(1,3-thiazol-4-yl)-1H-benzimidazole-5-sulfonamid...)
Affinity DataKi:  50.9nMAssay Description:Inhibition of human recombinant full length CA1 expressed in Escherichia coli BL21 (DE3) by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50248167(2-(1,3-thiazol-4-yl)-1H-benzimidazole-5-sulfonamid...)
Affinity DataKi:  72.5nMAssay Description:Inhibition of human recombinant full length CA2 expressed in Escherichia coli BL21 (DE3) by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetCarbonic anhydrase 5A, mitochondrial(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50248167(2-(1,3-thiazol-4-yl)-1H-benzimidazole-5-sulfonamid...)
Affinity DataKi:  72.7nMAssay Description:Inhibition of human recombinant full length CA5A by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50248167(2-(1,3-thiazol-4-yl)-1H-benzimidazole-5-sulfonamid...)
Affinity DataKi:  73.2nMAssay Description:Inhibition of human recombinant full length CA7 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50248167(2-(1,3-thiazol-4-yl)-1H-benzimidazole-5-sulfonamid...)
Affinity DataKi:  424nMAssay Description:Inhibition of human recombinant full length CA14 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 13(Mouse)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50248167(2-(1,3-thiazol-4-yl)-1H-benzimidazole-5-sulfonamid...)
Affinity DataKi:  4.85E+3nMAssay Description:Inhibition of mouse recombinant full length CA13 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 3(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50248167(2-(1,3-thiazol-4-yl)-1H-benzimidazole-5-sulfonamid...)
Affinity DataKi:  3.45E+4nMAssay Description:Inhibition of human recombinant full length CA3 expressed in Escherichia coli BL21 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed