BDBM50248296 256U87 HCl::CHEBI:9919::VALACYCLOVIR HYDROCHLORIDE::Valacyclovir HCl::Valtrex

SMILES Cl.CC(C)[C@H](N)C(=O)OCCOCn1cnc2c1[nH]c(N)nc2=O

InChI Key InChIKey=ZCDDBUOENGJMLV-QRPNPIFTSA-N

Data  4 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50248296   

TargetATP-binding cassette sub-family C member 4(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50248296(256U87 HCl | CHEBI:9919 | VALACYCLOVIR HYDROCHLORI...)
Show SMILES Cl.CC(C)[C@H](N)C(=O)OCCOCn1cnc2c1[nH]c(N)nc2=O
Show InChI InChI=1S/C13H20N6O4.ClH/c1-7(2)8(14)12(21)23-4-3-22-6-19-5-16-9-10(19)17-13(15)18-11(9)20;/h5,7-8H,3-4,6,14H2,1-2H3,(H3,15,17,18,20);1H/t8-;/m0./s1
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50248296(256U87 HCl | CHEBI:9919 | VALACYCLOVIR HYDROCHLORI...)
Show SMILES Cl.CC(C)[C@H](N)C(=O)OCCOCn1cnc2c1[nH]c(N)nc2=O
Show InChI InChI=1S/C13H20N6O4.ClH/c1-7(2)8(14)12(21)23-4-3-22-6-19-5-16-9-10(19)17-13(15)18-11(9)20;/h5,7-8H,3-4,6,14H2,1-2H3,(H3,15,17,18,20);1H/t8-;/m0./s1
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 3(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50248296(256U87 HCl | CHEBI:9919 | VALACYCLOVIR HYDROCHLORI...)
Show SMILES Cl.CC(C)[C@H](N)C(=O)OCCOCn1cnc2c1[nH]c(N)nc2=O
Show InChI InChI=1S/C13H20N6O4.ClH/c1-7(2)8(14)12(21)23-4-3-22-6-19-5-16-9-10(19)17-13(15)18-11(9)20;/h5,7-8H,3-4,6,14H2,1-2H3,(H3,15,17,18,20);1H/t8-;/m0./s1
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
TargetBile salt export pump(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50248296(256U87 HCl | CHEBI:9919 | VALACYCLOVIR HYDROCHLORI...)
Show SMILES Cl.CC(C)[C@H](N)C(=O)OCCOCn1cnc2c1[nH]c(N)nc2=O
Show InChI InChI=1S/C13H20N6O4.ClH/c1-7(2)8(14)12(21)23-4-3-22-6-19-5-16-9-10(19)17-13(15)18-11(9)20;/h5,7-8H,3-4,6,14H2,1-2H3,(H3,15,17,18,20);1H/t8-;/m0./s1
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair