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BDBM50248845 CHEMBL516191::N-(4-tert-Butylbenzyl)-N'-[7-methoxy-6-(methylsulfonylamino)-1,2,3,4-tetrahydro-1-naphthyl]thiourea

SMILES: COc1cc2C(CCCc2cc1NS(C)(=O)=O)NC(=S)NCc1ccc(cc1)C(C)(C)C

InChI Key: InChIKey=ZZWURKKCOBTTRB-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50248845   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vanilloid receptor


(Rattus norvegicus (rat))
BDBM50248845
PNG
(CHEMBL516191 | N-(4-tert-Butylbenzyl)-N'-[7-methox...)
Show SMILES COc1cc2C(CCCc2cc1NS(C)(=O)=O)NC(=S)NCc1ccc(cc1)C(C)(C)C
Show InChI InChI=1S/C24H33N3O3S2/c1-24(2,3)18-11-9-16(10-12-18)15-25-23(31)26-20-8-6-7-17-13-21(27-32(5,28)29)22(30-4)14-19(17)20/h9-14,20,27H,6-8,15H2,1-5H3,(H2,25,26,31)
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MMDB

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PC sid
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Similars

Article
PubMed
6.90E+3n/an/an/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Displacement of [3H]resiniferatoxin from rat TRPV1 expressed in CHO cells by scintillation counting


Eur J Med Chem 44: 322-31 (2008)


Article DOI: 10.1016/j.ejmech.2008.02.026
BindingDB Entry DOI: 10.7270/Q2R49QJ3
More data for this
Ligand-Target Pair