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BDBM50248893 CHEMBL4104431

SMILES: FC(F)(F)Oc1ccc(cc1)-c1nc(\C=C2/SC(=S)NC2=O)cs1

InChI Key: InChIKey=SCXFSQBJXAMPGL-YHYXMXQVSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50248893   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase pim-1


(Homo sapiens (Human))
BDBM50248893
PNG
(CHEMBL4104431)
Show SMILES FC(F)(F)Oc1ccc(cc1)-c1nc(\C=C2/SC(=S)NC2=O)cs1
Show InChI InChI=1S/C14H7F3N2O2S3/c15-14(16,17)21-9-3-1-7(2-4-9)12-18-8(6-23-12)5-10-11(20)19-13(22)24-10/h1-6H,(H,19,20,22)/b10-5-
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 2.90n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assay


Bioorg Med Chem 25: 2657-2665 (2017)


BindingDB Entry DOI: 10.7270/Q2CV4M5V
More data for this
Ligand-Target Pair