BDBM50250136 CHEMBL4095596
SMILES CC(CCCCCC(=O)NO)n1cc(cn1)-c1ncnc2[nH]ccc12
InChI Key InChIKey=RTLKDFQWSQARBW-UHFFFAOYSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50250136
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of HDAC9 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of C-terminal GST tagged human recombinant HDAC2 (1 to 488 residues) expressed in Baculovirus infected insect cells in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of C-terminal FLAG His tagged full length human recombinant HDAC1 (1 to 482 residues) expressed in baculovirus infected sf21 cells using R...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
National University Of Singapore
Curated by ChEMBL
National University Of Singapore
Curated by ChEMBL
Affinity DataIC50: 144nMAssay Description:Inhibition of human TYK2 using KKSRGDYMTMQIG as substrate in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
National University Of Singapore
Curated by ChEMBL
National University Of Singapore
Curated by ChEMBL
Affinity DataIC50: 436nMAssay Description:Inhibition of human JAK3 using GEEEEYFELVKKKK as substrate in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
National University Of Singapore
Curated by ChEMBL
National University Of Singapore
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] as substrate in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore
Curated by ChEMBL
National University Of Singapore
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] as substrate in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of C-terminal His tagged human recombinant HDAC8 (1 to 377 residues) expressed in Baculovirus infected insect cells in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of C-terminal His tagged human recombinant HDAC5 (657 to 1123 residues) expressed in Baculovirus infected insect cells in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal GST tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected insect cells using RHKKAc as substrate in pres...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
National University Of Singapore
Curated by ChEMBL
National University Of Singapore
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of human HDAC10 using fluorogenic peptide from p53 residues 379 to 382 as substrate in presence of ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
National University Of Singapore
Curated by ChEMBL
National University Of Singapore
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human JAK1 using poly[Glu:Tyr] as substrate in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair