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BDBM50251199 CHEMBL4062257

SMILES: CC1CN(CC(C)N1)C(=O)c1nc(Nc2cc(C)[nH]n2)c2cc(Cl)ccc2n1

InChI Key: InChIKey=DCSCGJBLXPXCMB-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251199   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase PAK 4


(Homo sapiens (Human))
BDBM50251199
PNG
(CHEMBL4062257)
Show SMILES CC1CN(CC(C)N1)C(=O)c1nc(Nc2cc(C)[nH]n2)c2cc(Cl)ccc2n1
Show InChI InChI=1S/C19H22ClN7O/c1-10-6-16(26-25-10)23-17-14-7-13(20)4-5-15(14)22-18(24-17)19(28)27-8-11(2)21-12(3)9-27/h4-7,11-12,21H,8-9H2,1-3H3,(H2,22,23,24,25,26)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
PubMed
119n/an/an/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human PAK4 kinase domain using coumarin and fluorescein-labeled ser/thr20 peptide as substrate preincubated for 15 mins followed by ATP...


J Med Chem 61: 265-285 (2018)


BindingDB Entry DOI: 10.7270/Q2BK1FSN
More data for this
Ligand-Target Pair