BDBM50252131 4-{trans-4-[4-(1H-Indol-3-yl)cyclohexyl]-piperazin-1-yl}-2-(trifluoromethyl)-1H-benzimidazole::CHEMBL520265

SMILES FC(F)(F)c1nc2c(cccc2[nH]1)N1CCN(CC1)[C@H]1CC[C@@H](CC1)c1c[nH]c2ccccc12

InChI Key InChIKey=XZYMEGJUWOQMQM-IYARVYRRSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50252131   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50252131(4-{trans-4-[4-(1H-Indol-3-yl)cyclohexyl]-piperazin...)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50252131(4-{trans-4-[4-(1H-Indol-3-yl)cyclohexyl]-piperazin...)
Affinity DataKi:  75nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5HTT reuptake siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed