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BDBM50253387 CHEMBL492665::N2,N4-dimethyl-N2,N4-diisobutyl-(6-styryl-pyrimidin-2,4-yl)-diamine

SMILES: CC(C)CN(C)c1cc(\C=C\c2ccccc2)nc(n1)N(C)CC(C)C

InChI Key: InChIKey=VMAHMBCEBLBIKJ-OUKQBFOZSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50253387   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Estrogen receptor


(Homo sapiens (Human))
BDBM50253387
PNG
(CHEMBL492665 | N2,N4-dimethyl-N2,N4-diisobutyl-(6-...)
Show SMILES CC(C)CN(C)c1cc(\C=C\c2ccccc2)nc(n1)N(C)CC(C)C
Show InChI InChI=1S/C22H32N4/c1-17(2)15-25(5)21-14-20(13-12-19-10-8-7-9-11-19)23-22(24-21)26(6)16-18(3)4/h7-14,17-18H,15-16H2,1-6H3/b13-12+
PDB

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UniProtKB/TrEMBL

antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+6n/an/an/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Binding affinity to ERalpha (unknown origin) assessed as inhibition of fluorescein-labeled nuclear receptor domain of steroid receptor coactivator 3 ...


J Med Chem 51: 6512-30 (2008)


Article DOI: 10.1021/jm800698b
BindingDB Entry DOI: 10.7270/Q2KD1XRF
More data for this
Ligand-Target Pair
Estradiol receptor beta (ERβ)


(Homo sapiens (Human))
BDBM50253387
PNG
(CHEMBL492665 | N2,N4-dimethyl-N2,N4-diisobutyl-(6-...)
Show SMILES CC(C)CN(C)c1cc(\C=C\c2ccccc2)nc(n1)N(C)CC(C)C
Show InChI InChI=1S/C22H32N4/c1-17(2)15-25(5)21-14-20(13-12-19-10-8-7-9-11-19)23-22(24-21)26(6)16-18(3)4/h7-14,17-18H,15-16H2,1-6H3/b13-12+
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+6n/an/an/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Binding affinity to ERbeta (unknown origin) assessed as inhibition of fluorescein-labeled nuclear receptor domain of steroid receptor coactivator 3 b...


J Med Chem 51: 6512-30 (2008)


Article DOI: 10.1021/jm800698b
BindingDB Entry DOI: 10.7270/Q2KD1XRF
More data for this
Ligand-Target Pair