BDBM50253393 CHEMBL495327::Naphthalene-2-carboxylic acid (4-{2-[((S)-2-amino-4,5,6,7-tetrahydro-benzothiazol-6-yl)-propyl-amino]-ethyl}-cyclohexyl)-amide

SMILES CCCN(CC[C@H]1CC[C@@H](CC1)NC(=O)c1ccc2ccccc2c1)[C@H]1CCc2nc(N)sc2C1

InChI Key InChIKey=QKVIHOUAEYBMIJ-OPXMRZJTSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50253393   

TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50253393(CHEMBL495327 | Naphthalene-2-carboxylic acid (4-{2...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]PD128907 from dopamine D3 receptor in Sprague-Dawley rat ventral striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50253393(CHEMBL495327 | Naphthalene-2-carboxylic acid (4-{2...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]R(+)-7-OH-DPAT from Sprague-Dawley rat dopamine D3 receptor after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50253393(CHEMBL495327 | Naphthalene-2-carboxylic acid (4-{2...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-R(+)-7-OHDPAT from dopamine D3 receptor in rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50253393(CHEMBL495327 | Naphthalene-2-carboxylic acid (4-{2...)
Affinity DataKi:  307nMAssay Description:Displacement of [3H]Spiperone from D2 receptor in Sprague-Dawley rat caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50253393(CHEMBL495327 | Naphthalene-2-carboxylic acid (4-{2...)
Affinity DataKi:  3.40E+3nMAssay Description:Displacement of [3H]SCH23390 from D1-like receptor in Sprague-Dawley rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed