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BDBM50253906 3-(4-(4-Fluorophenyl)-5-(2-(isopropylamino)pyridin-4-yl)-1Himidazol-2-ylthio)propane-1,2-diol::CHEMBL459716

SMILES: CC(C)Nc1cc(ccn1)-c1nc(SCC(O)CO)[nH]c1-c1ccc(F)cc1

InChI Key: InChIKey=TZUIGVDFKLFBTP-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50253906   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50253906
PNG
(3-(4-(4-Fluorophenyl)-5-(2-(isopropylamino)pyridin...)
Show SMILES CC(C)Nc1cc(ccn1)-c1nc(SCC(O)CO)[nH]c1-c1ccc(F)cc1
Show InChI InChI=1S/C20H23FN4O2S/c1-12(2)23-17-9-14(7-8-22-17)19-18(13-3-5-15(21)6-4-13)24-20(25-19)28-11-16(27)10-26/h3-9,12,16,26-27H,10-11H2,1-2H3,(H,22,23)(H,24,25)
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Article
PubMed
n/an/a 3n/an/an/an/an/an/a



Eberhard-Karls University of Tübingen

Curated by ChEMBL


Assay Description
Inhibition of p38alpha (unknown origin)


J Med Chem 51: 5630-40 (2008)


Article DOI: 10.1021/jm800373t
BindingDB Entry DOI: 10.7270/Q2XS5V6V
More data for this
Ligand-Target Pair