BDBM50254855 7-methyl-3-propyl-1-(pyridin-3-ylmethyl)-1H-imidazo[1,2-a]purine-2,4(3H,8H)-dione hydrochloride::CHEMBL465089

SMILES CCCn1c(=O)n(Cc2cccnc2)c2nc3[nH]c(C)cn3c2c1=O

InChI Key InChIKey=WWYGZOMPIIJQPI-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50254855   

TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254855(7-methyl-3-propyl-1-(pyridin-3-ylmethyl)-1H-imidaz...)
Affinity DataKi:  57nMAssay Description:Displacement of [3H]MRE3008F20 from human cloned adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254855(7-methyl-3-propyl-1-(pyridin-3-ylmethyl)-1H-imidaz...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]ZM241385 from human cloned adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254855(7-methyl-3-propyl-1-(pyridin-3-ylmethyl)-1H-imidaz...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]DPCPX from human cloned adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254855(7-methyl-3-propyl-1-(pyridin-3-ylmethyl)-1H-imidaz...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human cloned adenosine A2B cells expressed in CHO cells assessed as inhibition of NECA-stimulated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed