BDBM50255178 CHEMBL4079910
SMILES NC(=O)c1cnc(N[C@H]2CCCNC2)c2cc(sc12)-c1ccsc1
InChI Key InChIKey=LCAGMBOQRJACFN-NSHDSACASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50255178
Affinity DataIC50: 6nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by patch clamp assayMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as abrogation of camptothecin-induced G2/M phase arrestMore data for this Ligand-Target Pair