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BDBM50255504 CHEMBL4064083

SMILES: CC(C)S(=O)(=O)c1c(Cl)ccc(NC(=O)NC2CCC3CC23)c1O

InChI Key: InChIKey=FCUJJUONMWBUFF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50255504   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-X-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM50255504
PNG
(CHEMBL4064083)
Show SMILES CC(C)S(=O)(=O)c1c(Cl)ccc(NC(=O)NC2CCC3CC23)c1O
Show InChI InChI=1S/C16H21ClN2O4S/c1-8(2)24(22,23)15-11(17)4-6-13(14(15)20)19-16(21)18-12-5-3-9-7-10(9)12/h4,6,8-10,12,20H,3,5,7H2,1-2H3,(H2,18,19,21)
PDB

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Similars

Article
PubMed
n/an/a 25n/an/an/an/an/an/a



GSK Pharmaceuticals R & D

Curated by ChEMBL


Assay Description
Antagonist activity at TEV protease cleavage site linked GAL4-VP16-fused recombinant human CXCR2 expressed in cells assessed as inhibition of TEV pro...


J Med Chem 61: 2518-2532 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01854
BindingDB Entry DOI: 10.7270/Q2959M1F
More data for this
Ligand-Target Pair