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BDBM50256331 1-(3-(3-mesitylureido)-2-naphthamido)-4-oxocyclohexanecarboxylic acid::CHEMBL519942

SMILES: Cc1cc(C)c(NC(=O)Nc2cc3ccccc3cc2C(=O)NC2(CCC(=O)CC2)C(O)=O)c(C)c1

InChI Key: InChIKey=ZUUGDISHVJEEMF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50256331   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50256331
PNG
(1-(3-(3-mesitylureido)-2-naphthamido)-4-oxocyclohe...)
Show SMILES Cc1cc(C)c(NC(=O)Nc2cc3ccccc3cc2C(=O)NC2(CCC(=O)CC2)C(O)=O)c(C)c1
Show InChI InChI=1S/C28H29N3O5/c1-16-12-17(2)24(18(3)13-16)30-27(36)29-23-15-20-7-5-4-6-19(20)14-22(23)25(33)31-28(26(34)35)10-8-21(32)9-11-28/h4-7,12-15H,8-11H2,1-3H3,(H,31,33)(H,34,35)(H2,29,30,36)
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Similars

Article
PubMed
n/an/a 1.15E+3n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of human liver glycogen phosphorylase A by fluorescence intensity endpoint assay in presence of glucose


Bioorg Med Chem Lett 19: 976-80 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.085
BindingDB Entry DOI: 10.7270/Q26T0MGG
More data for this
Ligand-Target Pair