BDBM50256442 (S)-2-(3-(3-mesitylureido)-2-naphthamido)-3,3-dimethylbutanoic acid::CHEMBL475764

SMILES Cc1cc(C)c(NC(=O)Nc2cc3ccccc3cc2C(=O)N[C@H](C(O)=O)C(C)(C)C)c(C)c1

InChI Key InChIKey=WELDJBWSWBTAQE-HSZRJFAPSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50256442   

TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50256442((S)-2-(3-(3-mesitylureido)-2-naphthamido)-3,3-dime...)
Affinity DataIC50:  1.14E+3nMAssay Description:Inhibition of liver glycogen phosphorylase A in human HepG2 cells assessed as inhibition of forskolin-induced glucogenolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50256442((S)-2-(3-(3-mesitylureido)-2-naphthamido)-3,3-dime...)
Affinity DataIC50:  311nMAssay Description:Inhibition of human liver glycogen phosphorylase A by fluorescence plate reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50256442((S)-2-(3-(3-mesitylureido)-2-naphthamido)-3,3-dime...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed