BDBM50256444 (2S,3S)-2-(3-(3-mesitylureido)-2-naphthamido)-3-methylpentanoic acid::CHEMBL475766

SMILES CC[C@H](C)[C@H](NC(=O)c1cc2ccccc2cc1NC(=O)Nc1c(C)cc(C)cc1C)C(O)=O

InChI Key InChIKey=JEBJURUMASJIAQ-FYSMJZIKSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50256444   

TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50256444((2S,3S)-2-(3-(3-mesitylureido)-2-naphthamido)-3-me...)
Affinity DataIC50:  688nMAssay Description:Inhibition of liver glycogen phosphorylase A in human HepG2 cells assessed as inhibition of forskolin-induced glucogenolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50256444((2S,3S)-2-(3-(3-mesitylureido)-2-naphthamido)-3-me...)
Affinity DataIC50:  72nMAssay Description:Inhibition of human liver glycogen phosphorylase A by fluorescence plate reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50256444((2S,3S)-2-(3-(3-mesitylureido)-2-naphthamido)-3-me...)
Affinity DataIC50:  1.94E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed