BDBM50256668 (2S,3R)-3-cyclobutoxy-2-(3-(3-mesitylureido)-2-naphthamido)butanoic acid::CHEMBL473852

SMILES C[C@@H](OC1CCC1)[C@H](NC(=O)c1cc2ccccc2cc1NC(=O)Nc1c(C)cc(C)cc1C)C(O)=O

InChI Key InChIKey=VFXCDESXOOWVLU-BCHFMIIMSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50256668   

TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50256668((2S,3R)-3-cyclobutoxy-2-(3-(3-mesitylureido)-2-nap...)
Affinity DataIC50:  434nMAssay Description:Inhibition of liver glycogen phosphorylase A in human HepG2 cells assessed as inhibition of forskolin-induced glucogenolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50256668((2S,3R)-3-cyclobutoxy-2-(3-(3-mesitylureido)-2-nap...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human liver glycogen phosphorylase A by fluorescence plate reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50256668((2S,3R)-3-cyclobutoxy-2-(3-(3-mesitylureido)-2-nap...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed