BDBM50257028 CHEMBL473650::N-(1-oxo-2-phenyl-1,2-dihydropyrido[2,3-e][1,2,4]triazolo[4,3-a]pyrazin-4-yl)benzamide

SMILES O=C(Nc1nc2ncccc2n2c1nn(-c1ccccc1)c2=O)c1ccccc1

InChI Key InChIKey=AAGFKZWKWAMJNP-UHFFFAOYSA-N

Data  4 KI

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50257028   

TargetAdenosine receptor A3(Homo sapiens (Human))
Universita di Firenze

Curated by ChEMBL
LigandPNGBDBM50257028(CHEMBL473650 | N-(1-oxo-2-phenyl-1,2-dihydropyrido...)
Show SMILES O=C(Nc1nc2ncccc2n2c1nn(-c1ccccc1)c2=O)c1ccccc1
Show InChI InChI=1S/C21H14N6O2/c28-20(14-8-3-1-4-9-14)24-18-19-25-27(15-10-5-2-6-11-15)21(29)26(19)16-12-7-13-22-17(16)23-18/h1-13H,(H,22,23,24,28)
Affinity DataKi:  70.3nMAssay Description:Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Homo sapiens (Human))
Universita di Firenze

Curated by ChEMBL
LigandPNGBDBM50257028(CHEMBL473650 | N-(1-oxo-2-phenyl-1,2-dihydropyrido...)
Show SMILES O=C(Nc1nc2ncccc2n2c1nn(-c1ccccc1)c2=O)c1ccccc1
Show InChI InChI=1S/C21H14N6O2/c28-20(14-8-3-1-4-9-14)24-18-19-25-27(15-10-5-2-6-11-15)21(29)26(19)16-12-7-13-22-17(16)23-18/h1-13H,(H,22,23,24,28)
Affinity DataKi:  70.3nMAssay Description:Antagonist activity at human adenosine A3 receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(BOVINE)
Universita di Firenze

Curated by ChEMBL
LigandPNGBDBM50257028(CHEMBL473650 | N-(1-oxo-2-phenyl-1,2-dihydropyrido...)
Show SMILES O=C(Nc1nc2ncccc2n2c1nn(-c1ccccc1)c2=O)c1ccccc1
Show InChI InChI=1S/C21H14N6O2/c28-20(14-8-3-1-4-9-14)24-18-19-25-27(15-10-5-2-6-11-15)21(29)26(19)16-12-7-13-22-17(16)23-18/h1-13H,(H,22,23,24,28)
Affinity DataKi:  152nMAssay Description:Displacement of [3H]DPCPX from bovine brain cortical membrane adenosine A1 receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universita di Firenze

Curated by ChEMBL
LigandPNGBDBM50257028(CHEMBL473650 | N-(1-oxo-2-phenyl-1,2-dihydropyrido...)
Show SMILES O=C(Nc1nc2ncccc2n2c1nn(-c1ccccc1)c2=O)c1ccccc1
Show InChI InChI=1S/C21H14N6O2/c28-20(14-8-3-1-4-9-14)24-18-19-25-27(15-10-5-2-6-11-15)21(29)26(19)16-12-7-13-22-17(16)23-18/h1-13H,(H,22,23,24,28)
Affinity DataKi:  2.24E+3nMAssay Description:Displacement of [3H]NECA from human cloned adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair