BDBM50257382 CHEMBL493514::ethyl 4-methyl-2-(4-(methyl(3,4,5-trimethoxybenzyl)amino)-6-(piperazin-1-yl)pyrimidin-2-ylamino)thiazole-5-carboxylate

SMILES CCOC(=O)c1sc(Nc2nc(cc(n2)N2CCNCC2)N(C)Cc2cc(OC)c(OC)c(OC)c2)nc1C

InChI Key InChIKey=CELAACRDIWTXLD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50257382   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50257382(CHEMBL493514 | ethyl 4-methyl-2-(4-(methyl(3,4,5-t...)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed