BDBM50257444 CHEMBL492548::ethyl 2-(4-(3-carbamoylpiperazin-1-yl)-6-(4-(dimethylamino)piperidin-1-yl)pyrimidin-2-ylamino)-4-methylthiazole-5-carboxylate

SMILES CCOC(=O)c1sc(Nc2nc(cc(n2)N2CCNC(C2)C(N)=O)N2CCC(CC2)N(C)C)nc1C

InChI Key InChIKey=KNESPDCWRWRWAG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50257444   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50257444(CHEMBL492548 | ethyl 2-(4-(3-carbamoylpiperazin-1-...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed