BDBM50257963 2-(3-chlorobenzyloxy)-6-(piperazin-1-yl)pyrazine::CHEMBL494947
SMILES Clc1cccc(COc2cncc(n2)N2CCNCC2)c1
InChI Key InChIKey=PCWGGOVOEWHPMG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50257963
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity to 5-HT2C receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 9.30nMAssay Description:Displacement of [3H]mesulergine from human 5HT2C receptor expressed in tsA201 cell membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataKi: 81nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in tsA201 cell membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 140nMAssay Description:Agonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as accumulation of IP1 incubated for 1 hr at 37 degC followed by 15 mins ...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 76nMAssay Description:Agonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as induction of intracellular calcium release measured for 90 secs by flu...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 8.10nMAssay Description:Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as accumulation of IP1 incubated for 1 hr at 37 degC followed by 15 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataEC50: 65nMAssay Description:Agonist activity at 5HT2B receptor (unknown origin) relative to controlMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 0.110nMAssay Description:Agonist activity at 5HT2C receptor (unknown origin) relative to controlMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 1.90nMAssay Description:Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as induction of intracellular calcium release measured for 90 secs by flu...More data for this Ligand-Target Pair