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BDBM50258911 CHEMBL4103219

SMILES: CCC(NC(=O)N1CC(=O)Nc2cccnc12)c1ccccc1OC(F)(F)F

InChI Key: InChIKey=YZKROCYBXRODTL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50258911   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Homo sapiens phosphodiesterase 2A (PDE2A)


(Homo sapiens (Human))
BDBM50258911
PNG
(CHEMBL4103219)
Show SMILES CCC(NC(=O)N1CC(=O)Nc2cccnc12)c1ccccc1OC(F)(F)F
Show InChI InChI=1S/C18H17F3N4O3/c1-2-12(11-6-3-4-8-14(11)28-18(19,20)21)24-17(27)25-10-15(26)23-13-7-5-9-22-16(13)25/h3-9,12H,2,10H2,1H3,(H,23,26)(H,24,27)
PDB

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antibodypedia
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PC cid
PC sid
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Similars

PubMed
n/an/a 8.10E+3n/an/an/an/an/an/a



Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of recombinant human full-length His-tagged PDE2A3 expressed in fall armyworm Sf9 cells using [3H]cGMP as substrate preincubated for 30 mi...


J Med Chem 60: 7677-7702 (2017)


BindingDB Entry DOI: 10.7270/Q2P271JR
More data for this
Ligand-Target Pair