BDBM50259055 8-((2-chloro-4-methylphenyl)(2-chlorophenyl)methyl)-3-((5-methoxypyridin-2-yl)methyl)-8-azabicyclo[3.2.1]octan-3-ol::CHEMBL466066

SMILES COc1ccc(CC2(O)CC3CCC(C2)N3C(c2ccccc2Cl)c2ccc(C)cc2Cl)nc1

InChI Key InChIKey=FCAIKVZTCKWJCO-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50259055   

TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259055(8-((2-chloro-4-methylphenyl)(2-chlorophenyl)methyl...)
Affinity DataKi:  13nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human cloned NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259055(8-((2-chloro-4-methylphenyl)(2-chlorophenyl)methyl...)
Affinity DataKi:  384nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259055(8-((2-chloro-4-methylphenyl)(2-chlorophenyl)methyl...)
Affinity DataEC50:  90nMAssay Description:Agonist activity at human NOP assessed as stimulation of GDP-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed