BDBM50259101 3-(8-((2-chloro-4-methylphenyl)(2-chlorophenyl)methyl)-3-hydroxy-8-azabicyclo[3.2.1]octan-3-yl)pyrrolidin-2-one::CHEMBL506634

SMILES Cc1ccc(C(N2C3CCC2CC(O)(C3)C2CCNC2=O)c2ccccc2Cl)c(Cl)c1

InChI Key InChIKey=ZVWINNTVUYULMY-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50259101   

TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259101(3-(8-((2-chloro-4-methylphenyl)(2-chlorophenyl)met...)
Affinity DataKi:  3.60nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human cloned NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259101(3-(8-((2-chloro-4-methylphenyl)(2-chlorophenyl)met...)
Affinity DataKi:  781nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259101(3-(8-((2-chloro-4-methylphenyl)(2-chlorophenyl)met...)
Affinity DataEC50:  48nMAssay Description:Agonist activity at human NOP assessed as stimulation of GDP-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed