BDBM50259147 8-(bis(2-chlorophenyl)methyl)-3-methoxy-3-phenyl-8-azabicyclo[3.2.1]octane::CHEMBL512950

SMILES COC1(CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl)c1ccccc1

InChI Key InChIKey=ZCNMZJMGPQGLKK-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50259147   

TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259147(8-(bis(2-chlorophenyl)methyl)-3-methoxy-3-phenyl-8...)
Affinity DataKi:  8nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human cloned NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259147(8-(bis(2-chlorophenyl)methyl)-3-methoxy-3-phenyl-8...)
Affinity DataKi:  636nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259147(8-(bis(2-chlorophenyl)methyl)-3-methoxy-3-phenyl-8...)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human NOP assessed as stimulation of GDP-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259147(8-(bis(2-chlorophenyl)methyl)-3-methoxy-3-phenyl-8...)
Affinity DataEC50:  545nMAssay Description:Agonist activity at human mu opioid assessed as stimulation of GDP-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed