BDBM50261196 1-{2-[(1S)-(3-Azetidinylcarboxamido)-2-methylpropyl]-6-fluorophenyl}-4-[(2R)-methyl-3-(2-methoxy-4-chlorophenyl)propionyl]piperazine::CHEMBL521715

SMILES COc1cc(Cl)ccc1C[C@@H](C)C(=O)N1CCN(CC1)c1c(F)cccc1[C@@H](NC(=O)C1CNC1)C(C)C

InChI Key InChIKey=XWVUILPYFRWOKA-BCHFMIIMSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50261196   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50261196(1-{2-[(1S)-(3-Azetidinylcarboxamido)-2-methylpropy...)
Affinity DataKi:  3.10nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50261196(1-{2-[(1S)-(3-Azetidinylcarboxamido)-2-methylpropy...)
Affinity DataIC50:  42nMAssay Description:Antagonist activity at human MC4R expressed in CHO cells assessed as inhibition of alpha-MSH-induced cAMP production by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed