BDBM50261257 CHEMBL4099854
SMILES COc1cc(Nc2nccc3nc([nH]c23)-c2c(Cl)cccc2Cl)ncn1
InChI Key InChIKey=OANXOEXNBCTCLW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50261257
Affinity DataKi: 0.700nMAssay Description:Inhibition of TYK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Inhibition of JAK2 (unknown origin) assessed as reduction in EPO-mediated STAT5 phosphorylation by cell based readout assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.60E+3nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 6.50E+3nMAssay Description:Inhibition of JAK2 (unknown origin) assessed as reduction in EPO-mediated STAT5 phosphorylation by cell based readout assayMore data for this Ligand-Target Pair