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BDBM50263897 4-benzyl-N-methyl-N-(2-(piperidin-1-yl)ethyl)piperidine-1-carboxamide::CHEMBL489580

SMILES: CN(CCN1CCCCC1)C(=O)N1CCC(Cc2ccccc2)CC1

InChI Key: InChIKey=XSCNGNHXXLTFCK-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50263897   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50263897
PNG
(4-benzyl-N-methyl-N-(2-(piperidin-1-yl)ethyl)piper...)
Show SMILES CN(CCN1CCCCC1)C(=O)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C21H33N3O/c1-22(16-17-23-12-6-3-7-13-23)21(25)24-14-10-20(11-15-24)18-19-8-4-2-5-9-19/h2,4-5,8-9,20H,3,6-7,10-18H2,1H3
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Similars

Article
PubMed
n/an/a 393n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of (R)-alpha-methylhistamine-induced [35S]GTPgammaS binding


Bioorg Med Chem Lett 18: 5101-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.125
BindingDB Entry DOI: 10.7270/Q2PC3268
More data for this
Ligand-Target Pair