BDBM50264546 CHEMBL4094874::US10005735, Table 1.3

SMILES Sc1cccc2ccccc12

InChI Key InChIKey=SEXOVMIIVBKGGM-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50264546   

Target26S proteasome non-ATPase regulatory subunit 14(Homo sapiens (Human))
California Institute of Technology

US Patent
LigandPNGBDBM50264546(CHEMBL4094874 | US10005735, Table 1.3)
Show SMILES Sc1cccc2ccccc12
Show InChI InChI=1S/C10H8S/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H
Affinity DataIC50: 1.00E+5nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
Target26S proteasome non-ATPase regulatory subunit 14(Homo sapiens (Human))
California Institute of Technology

US Patent
LigandPNGBDBM50264546(CHEMBL4094874 | US10005735, Table 1.3)
Show SMILES Sc1cccc2ccccc12
Show InChI InChI=1S/C10H8S/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated ...More data for this Ligand-Target Pair