BDBM50264809 2-((4-phenoxyphenylsulfonyl)methyl)thiirane::CHEMBL483857::Thiirane (deuterium), 1-d2::Thiirane, 1::US10357546, SB-3CT
SMILES O=S(=O)(CC1CS1)c1ccc(Oc2ccccc2)cc1
InChI Key InChIKey=LSONWRHLFZYHIN-UHFFFAOYSA-N
Data 33 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 33 hits for monomerid = 50264809
Affinity DataKi: 13.9nMAssay Description:Competitive inhibition of human MMP2 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of recombinant human MMP2 expressed in human HeLaS3 cells using MOCAcPLGLA2pr(Dnp)-AR-NH2 as substrate incubated for 15 to 30 mins by fluo...More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of MMP2 by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Inhibition of recombinant human MMP2More data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Competitive inhibition of human MMP14 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 64nMAssay Description:Inhibition assay using matrix metalloproteinase (MMP-2).Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Inhibition of MMP-14 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 320nMAssay Description:Inhibition assay using matrix metalloproteinase (MMP-2).Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Inhibition of recombinant human MMP9More data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Human recombinant active MMP-2 and MMP-7, and the catalytic domains of MMP-3 and MMP-14/MT1-MMP were purchased from EMD Chemicals, Inc. (San Diego, C...More data for this Ligand-Target Pair
Affinity DataKi: 600nMAssay Description:Inhibition of recombinant human MMP9 expressed in human HeLaS3 cells using MOCAcPLGLA2pr(Dnp)-AR-NH2 as substrate incubated for 15 to 30 mins by fluo...More data for this Ligand-Target Pair
Affinity DataKi: 600nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 600nMAssay Description:Competitive inhibition of human MMP9 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.10E+3nMAssay Description:Human recombinant active MMP-2 and MMP-7, and the catalytic domains of MMP-3 and MMP-14/MT1-MMP were purchased from EMD Chemicals, Inc. (San Diego, C...More data for this Ligand-Target Pair
Affinity DataKi: 2.10E+3nMAssay Description:Non-competitive inhibition of MMP8 (unknown origin)More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataKi: 4.00E+3nMAssay Description:Inhibition of MMP-3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.50E+4nMAssay Description:Inhibition of human recombinant MMP3 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+4nMAssay Description:Competitive inhibition of human MMP3 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6.70E+4nMAssay Description:Inhibition of MMP-7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 7.30E+4nMAssay Description:Inhibition of MMP-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 9.60E+4nMAssay Description:Competitive inhibition of human MMP7 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 9.60E+4nMAssay Description:Inhibition of human recombinant MMP7 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 2.06E+5nMAssay Description:Inhibition of human recombinant MMP1 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 2.06E+5nMAssay Description:Competitive inhibition of human MMP1 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair