BDBM50265464 4-(5-(4-chlorophenyl)-4-(pyridin-3-yl)-1H-imidazol-2-yl)phenol::CHEMBL509750::NSC-683634

SMILES Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccc(Cl)cc1)-c1cccnc1

InChI Key InChIKey=GOSRVAHFGDUDAX-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265464   

TargetAromatase(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50265464(4-(5-(4-chlorophenyl)-4-(pyridin-3-yl)-1H-imidazol...)
Affinity DataKi:  15.1nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by Lineweaver-Burk plot in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50265464(4-(5-(4-chlorophenyl)-4-(pyridin-3-yl)-1H-imidazol...)
Affinity DataIC50:  47.7nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by liquid scintillation counting in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed