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BDBM50265909 CHEMBL4082057

SMILES: Cc1nn(-c2ccccn2)c2cc(ccc12)-c1ccc(cc1)[C@H]1C[C@H]1C(O)=O

InChI Key: InChIKey=ZOCRWTIQNIUCSG-WOJBJXKFSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265909   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM50265909
PNG
(CHEMBL4082057)
Show SMILES Cc1nn(-c2ccccn2)c2cc(ccc12)-c1ccc(cc1)[C@H]1C[C@H]1C(O)=O
Show InChI InChI=1S/C23H19N3O2/c1-14-18-10-9-17(12-21(18)26(25-14)22-4-2-3-11-24-22)15-5-7-16(8-6-15)19-13-20(19)23(27)28/h2-12,19-20H,13H2,1H3,(H,27,28)/t19-,20-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.70E+4n/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Agonist activity at human GPR120 expressed in CHO-FlpIn cells after 15 mins by DMR assay


J Med Chem 60: 3187-3197 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00210
BindingDB Entry DOI: 10.7270/Q2PZ5C9Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Mus musculus)
BDBM50265909
PNG
(CHEMBL4082057)
Show SMILES Cc1nn(-c2ccccn2)c2cc(ccc12)-c1ccc(cc1)[C@H]1C[C@H]1C(O)=O
Show InChI InChI=1S/C23H19N3O2/c1-14-18-10-9-17(12-21(18)26(25-14)22-4-2-3-11-24-22)15-5-7-16(8-6-15)19-13-20(19)23(27)28/h2-12,19-20H,13H2,1H3,(H,27,28)/t19-,20-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.90E+4n/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR40 expressed in HEK293 cells assessed as increase in intracellular calcium level after 5 mins by FLUO-4-AM dye-based FLI...


J Med Chem 60: 3187-3197 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00210
BindingDB Entry DOI: 10.7270/Q2PZ5C9Z
More data for this
Ligand-Target Pair