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BDBM50265946 2-(1-(4-(1-(4-methoxyphenyl)-7-oxo-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazolo[3,4-c]pyridin-6(7H)-yl)phenyl)cyclopropyl)acetamide::CHEMBL467576

SMILES: COc1ccc(cc1)-n1nc(c2CCN(C(=O)c12)c1ccc(cc1)C1(CC(N)=O)CC1)C(F)(F)F

InChI Key: InChIKey=DLDUFCSSPIXLKT-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50265946   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50265946
PNG
(2-(1-(4-(1-(4-methoxyphenyl)-7-oxo-3-(trifluoromet...)
Show SMILES COc1ccc(cc1)-n1nc(c2CCN(C(=O)c12)c1ccc(cc1)C1(CC(N)=O)CC1)C(F)(F)F
Show InChI InChI=1S/C25H23F3N4O3/c1-35-18-8-6-17(7-9-18)32-21-19(22(30-32)25(26,27)28)10-13-31(23(21)34)16-4-2-15(3-5-16)24(11-12-24)14-20(29)33/h2-9H,10-14H2,1H3,(H2,29,33)
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MMDB

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Similars

Article
PubMed
0.590n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Binding affinity to human coagulation factor 10a


Bioorg Med Chem Lett 19: 462-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.049
BindingDB Entry DOI: 10.7270/Q2M908HB
More data for this
Ligand-Target Pair