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BDBM50267349 CHEMBL4105518

SMILES: Clc1ccc(OCc2ccccc2)c(c1)C(=O)N[C@@H](Cc1ccccc1)C=O

InChI Key: InChIKey=UMSQBDSZIBHKTM-FQEVSTJZSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50267349   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proteasome subunit beta type-1/beta type-5


(Homo sapiens (Human))
BDBM50267349
PNG
(CHEMBL4105518)
Show SMILES Clc1ccc(OCc2ccccc2)c(c1)C(=O)N[C@@H](Cc1ccccc1)C=O
Show InChI InChI=1S/C23H20ClNO3/c24-19-11-12-22(28-16-18-9-5-2-6-10-18)21(14-19)23(27)25-20(15-26)13-17-7-3-1-4-8-17/h1-12,14-15,20H,13,16H2,(H,25,27)/t20-/m0/s1
PDB
MMDB

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Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Palack£ University & Institute of Experimental Botany ASCR

Curated by ChEMBL


Assay Description
Inhibition of chymotrypsin-like activity of 26S proteasome beta 5 subunit in human U266 cells using Suc-LLVY-aminoluciferin as substrate after 1 hr b...


Eur J Med Chem 135: 142-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.04.027
BindingDB Entry DOI: 10.7270/Q2WD432G
More data for this
Ligand-Target Pair