BDBM50267485 1-(4-(3-bromo-5-(trifluoromethyl)phenylsulfonyl)piperazin-1-yl)-2-(4-(trifluoromethyl)phenyl)ethanone::CHEMBL476254

SMILES FC(F)(F)c1ccc(CC(=O)N2CCN(CC2)S(=O)(=O)c2cc(Br)cc(c2)C(F)(F)F)cc1

InChI Key InChIKey=LDORSZCZJLCJQE-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50267485   

TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267485(1-(4-(3-bromo-5-(trifluoromethyl)phenylsulfonyl)pi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB2R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267485(1-(4-(3-bromo-5-(trifluoromethyl)phenylsulfonyl)pi...)
Affinity DataEC50:  1nMAssay Description:Inverse agonist activity at human recombinant CB1R expressed in CHO cells assessed as increase in forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267485(1-(4-(3-bromo-5-(trifluoromethyl)phenylsulfonyl)pi...)
Affinity DataIC50:  6nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed