BDBM50267581 (4Z)-4-[({[1-(3-Furyl)-2-oxo-1,2-dihydropyridin-4-yl]methyl}-amino)methylene]-6-iodoisoquinoline-1,3(2H,4H)-dione::CHEMBL490451
SMILES Ic1ccc2C(=O)NC(=O)C(=CNCc3ccn(-c4ccoc4)c(=O)c3)c2c1
InChI Key InChIKey=WYFUXDSMNLVNEA-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50267581
Affinity DataIC50: 370nMAssay Description:Inhibition of retinoblastoma susceptibility gene product phosphorylation in human MCF7 cells after 24 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin) assessed as inhibition of retinoblastoma susceptibility gene product phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of CDK1/Cyclin B1 (unknown origin) assessed as inhibition of retinoblastoma susceptibility gene product phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin) assessed as inhibition of retinoblastoma susceptibility gene product phosphorylationMore data for this Ligand-Target Pair