BDBM50268131 1-Ethyl-8-(4-(4-(4-fluorobenzyl)piperazine-1-sulfonyl)phenyl)-3,7-dihydropurine-2,6-dione::CHEMBL520297

SMILES CCn1c(=O)[nH]c2nc([nH]c2c1=O)-c1ccc(cc1)S(=O)(=O)N1CCN(Cc2ccc(F)cc2)CC1

InChI Key InChIKey=AQZAJVBRYMBFPK-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50268131   

TargetAdenosine receptor A2b(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50268131(1-Ethyl-8-(4-(4-(4-fluorobenzyl)piperazine-1-sulfo...)
Affinity DataKi:  1.27nMAssay Description:Displacement of [3H]PSB-603 from human recombinant adenosine A2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Institute

Curated by ChEMBL
LigandPNGBDBM50268131(1-Ethyl-8-(4-(4-(4-fluorobenzyl)piperazine-1-sulfo...)
Affinity DataKi:  40.2nMAssay Description:Displacement of [3H]MSX-2 from rat brain striatum adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50268131(1-Ethyl-8-(4-(4-(4-fluorobenzyl)piperazine-1-sulfo...)
Affinity DataKi:  92nMAssay Description:Displacement of [3H]MSX-2 from human recombinant adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Institute

Curated by ChEMBL
LigandPNGBDBM50268131(1-Ethyl-8-(4-(4-(4-fluorobenzyl)piperazine-1-sulfo...)
Affinity DataKi:  296nMAssay Description:Displacement of [3H]CCPA from rat brain cortex adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50268131(1-Ethyl-8-(4-(4-(4-fluorobenzyl)piperazine-1-sulfo...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]PSB-11 from human recombinant adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50268131(1-Ethyl-8-(4-(4-(4-fluorobenzyl)piperazine-1-sulfo...)
Affinity DataKi:  1.82E+3nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed