BDBM50268500 1-butyl-4-(2-(4'-ethylbiphenyl-3-yl)ethyl)-6-ethynyl-1H-indene::9-(3-hydroxypropyl)-6-((4'-methoxybiphenyl-3-yl)methylamino)-9H-purine-2-carbonitrile::CHEMBL524075

SMILES COc1ccc(cc1)-c1cccc(CNc2nc(nc3n(CCCO)cnc23)C#N)c1

InChI Key InChIKey=NASGVNPYCNAHQR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50268500   

TargetCathepsin B(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50268500(1-butyl-4-(2-(4'-ethylbiphenyl-3-yl)ethyl)-6-ethyn...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50268500(1-butyl-4-(2-(4'-ethylbiphenyl-3-yl)ethyl)-6-ethyn...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of California

Curated by ChEMBL
LigandPNGBDBM50268500(1-butyl-4-(2-(4'-ethylbiphenyl-3-yl)ethyl)-6-ethyn...)
Affinity DataIC50:  800nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed