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BDBM50268715 CHEMBL4090221

SMILES: CCN(Cc1cccs1)C(=O)C(C)Oc1ccc(C)cc1

InChI Key: InChIKey=GFHZQLLTXCWZJP-UHFFFAOYSA-N

Data: 1 EC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50268715   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily M member 8 (TRPM8)


(Homo sapiens (Human))
BDBM50268715
PNG
(CHEMBL4090221)
Show SMILES CCN(Cc1cccs1)C(=O)C(C)Oc1ccc(C)cc1
Show InChI InChI=1S/C17H21NO2S/c1-4-18(12-16-6-5-11-21-16)17(19)14(3)20-15-9-7-13(2)8-10-15/h5-11,14H,4,12H2,1-3H3
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PC cid
PC sid
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Similars

PubMed
n/an/an/an/a 889n/an/an/an/a



Senomyx Inc

Curated by ChEMBL


Assay Description
Agonist activity at human TRPM8 expressed in HEK293 cells assessed as increase in intracellular calcium level after 15 mins by Fluo-3-AM dye-based fl...


Bioorg Med Chem Lett 27: 3931-3938 (2017)


BindingDB Entry DOI: 10.7270/Q25H7JRG
More data for this
Ligand-Target Pair