BDBM50268906 (2S,3S,5RS)-N-hydroxy-5-(2-oxo-2-(pyrrolidin-1-yl)ethyl)-2-(4-phenylpiperazine-1-carbonyl)piperidine-3-carboxamide::CHEMBL495596
SMILES ONC(=O)[C@H]1CC(CC(=O)N2CCCC2)CN[C@@H]1C(=O)N1CCN(CC1)c1ccccc1
InChI Key InChIKey=JUKNHBAVDHQUJP-LMBAYHJBSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50268906
Affinity DataIC50: 28nMAssay Description:Inhibition of HER2 extracellular domain sheddase activity in human BT474 cells after 72 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human MMP2More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Incyte
Curated by ChEMBL
Incyte
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant ADAM10More data for this Ligand-Target Pair