BDBM50274439 4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]phenyl}-amino)-6-methoxy-7-[(1E)-4-(4-methylpiperazin-1-yl)but-1-enyl]quinoline-3-carbonitrile::CHEMBL524111
SMILES COc1cc2c(Nc3ccc(Sc4nccn4C)c(Cl)c3)c(cnc2cc1\C=C\CCN1CCN(C)CC1)C#N
InChI Key InChIKey=WXUNOFVLABNPNZ-GQCTYLIASA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50274439
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of MEK1 (unknown origin) by raf/MEK1/MAPK coupled assayMore data for this Ligand-Target Pair