BDBM50274698 4-(4-(1-ethyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-ylamino)-N-(2-methoxyethyl)benzenesulfonamide::CHEMBL485618

SMILES CCn1c(C)ncc1-c1ccnc(Nc2ccc(cc2)S(=O)(=O)NCCOC)n1

InChI Key InChIKey=KVJXNCXRESCVKS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50274698   

TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50274698(4-(4-(1-ethyl-2-methyl-1H-imidazol-5-yl)pyrimidin-...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50274698(4-(4-(1-ethyl-2-methyl-1H-imidazol-5-yl)pyrimidin-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed