BDBM50274891 (Z)-5-(Naphthalen-2'-ylmethylene)-2-thioxothiazolidin-4-one::CHEMBL456850

SMILES SC1=NC(=O)C(S1)=Cc1ccc2ccccc2c1

InChI Key InChIKey=ATGWUPYXIYFRKP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50274891   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50274891((Z)-5-(Naphthalen-2'-ylmethylene)-2-thioxothiazoli...)
Affinity DataIC50:  113nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 2(Mus musculus)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50274891((Z)-5-(Naphthalen-2'-ylmethylene)-2-thioxothiazoli...)
Affinity DataIC50:  2.69E+4nMAssay Description:Inhibition of mouse recombinant NAT2 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed