BDBM50275220 2-{2-[2-(3-Methoxyphenyl)ethyl]phenoxy}ethyl-4-(N-methyl)piperazine::CHEMBL487960

SMILES COc1cccc(CCc2ccccc2OCCN2CCN(C)CC2)c1

InChI Key InChIKey=QNUFXAULMIMQGB-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50275220   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50275220(2-{2-[2-(3-Methoxyphenyl)ethyl]phenoxy}ethyl-4-(N-...)
Affinity DataKi:  1.78E+5nMAssay Description:Displacement of [3H]spiroperidol from human cloned dopaminergic D2 receptor expressed in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50275220(2-{2-[2-(3-Methoxyphenyl)ethyl]phenoxy}ethyl-4-(N-...)
Affinity DataKi: >5.00E+6nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5-HT1A receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50275220(2-{2-[2-(3-Methoxyphenyl)ethyl]phenoxy}ethyl-4-(N-...)
Affinity DataIC50:  7.76E+3nMAssay Description:Inhibition of ABCB1 (unknown origin) transfected in MDCK cells assessed as increase in calcein-AM accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50275220(2-{2-[2-(3-Methoxyphenyl)ethyl]phenoxy}ethyl-4-(N-...)
Affinity DataIC50:  800nMAssay Description:Inhibition of ABCB1-mediated [3H]vinblastine transportation in human Caco2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed