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BDBM50275909 5-chloro-N-(4-phenoxybenzyl)pyrazolo[1,5-a]pyrimidin-7-amine::CHEMBL471193

SMILES: Clc1cc(NCc2ccc(Oc3ccccc3)cc2)n2nccc2n1

InChI Key: InChIKey=CMASVBJFCFMVDT-UHFFFAOYSA-N

Data: 1 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50275909   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Small conductance calcium-activated potassium channel protein 3 (KCa2.3)


(Homo sapiens (Human))
BDBM50275909
PNG
(5-chloro-N-(4-phenoxybenzyl)pyrazolo[1,5-a]pyrimid...)
Show SMILES Clc1cc(NCc2ccc(Oc3ccccc3)cc2)n2nccc2n1
Show InChI InChI=1S/C19H15ClN4O/c20-17-12-19(24-18(23-17)10-11-22-24)21-13-14-6-8-16(9-7-14)25-15-4-2-1-3-5-15/h1-12,21H,13H2
PDB

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Inhibition of Kca2.3 channel (unknown origin) expressed in HEK293 cells by thallium flux assay


Bioorg Med Chem Lett 18: 5694-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.026
BindingDB Entry DOI: 10.7270/Q2TM79Z6
More data for this
Ligand-Target Pair