BDBM50276487 1-(4-amino-2,6-diisopropylphenyl)-3-((1-(2-methoxyphenyl)-4-(3-methoxyphenyl)piperidin-4-yl)methyl)urea dihydrochloride::CHEMBL500498::CHEMBL576152

SMILES COc1cccc(c1)C1(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)CCN(CC1)c1ccccc1OC

InChI Key InChIKey=YSLRYIISBIFCMM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50276487   

TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50276487(1-(4-amino-2,6-diisopropylphenyl)-3-((1-(2-methoxy...)
Affinity DataIC50:  37nMAssay Description:Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50276487(1-(4-amino-2,6-diisopropylphenyl)-3-((1-(2-methoxy...)
Affinity DataIC50:  37nMAssay Description:Inhibition of ACAT in human HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed