BDBM50277935 (S)-2-(1-chloro-4-hydroxyisoquinoline-3-carboxamido)propanoic acid::CHEMBL485022

SMILES C[C@H](NC(=O)c1nc(Cl)c2ccccc2c1O)C(O)=O

InChI Key InChIKey=QJWFWOUODUTVCE-LURJTMIESA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277935   

TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50277935((S)-2-(1-chloro-4-hydroxyisoquinoline-3-carboxamid...)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50277935((S)-2-(1-chloro-4-hydroxyisoquinoline-3-carboxamid...)
Affinity DataIC50:  512nMAssay Description:Inhibition of human PHD2 at 293K temperature by solvent relaxation techniqueMore data for this Ligand-Target Pair