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BDBM50280260 7-{4-[3-(4-Chloro-benzenesulfonylamino)-propyl]-pyridin-3-yl}-heptanoic acid::CHEMBL297561

SMILES: OC(=O)CCCCCCc1cnccc1CCCNS(=O)(=O)c1ccc(Cl)cc1

InChI Key: InChIKey=UHRUKVZHDOYFTJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50280260   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Thromboxane A2 Synthase (P450 TxA2)


(Homo sapiens (Human))
BDBM50280260
PNG
(7-{4-[3-(4-Chloro-benzenesulfonylamino)-propyl]-py...)
Show SMILES OC(=O)CCCCCCc1cnccc1CCCNS(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H27ClN2O4S/c22-19-9-11-20(12-10-19)29(27,28)24-14-5-7-17-13-15-23-16-18(17)6-3-1-2-4-8-21(25)26/h9-13,15-16,24H,1-8,14H2,(H,25,26)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 15n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration of the compound against thromboxane synthase enzyme


Bioorg Med Chem Lett 2: 1619-1622 (1992)


Article DOI: 10.1016/S0960-894X(00)80442-4
BindingDB Entry DOI: 10.7270/Q2BC3ZF2
More data for this
Ligand-Target Pair