BDBM50281126 1-(3-tert-Butyl-phenyl)-2,2,2-trifluoro-ethanone::CHEMBL89354

SMILES CC(C)(C)c1cccc(c1)C(=O)C(F)(F)F

InChI Key InChIKey=XAZQUPBUJONHAF-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50281126   

TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
TBA

Curated by ChEMBL
LigandPNGBDBM50281126(1-(3-tert-Butyl-phenyl)-2,2,2-trifluoro-ethanone |...)
Affinity DataKi:  0.00370nMAssay Description:Tested for the ability to inhibit Acetylcholinesterase (AChE) from Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetylcholinesterase(Anopheles gambiae)
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50281126(1-(3-tert-Butyl-phenyl)-2,2,2-trifluoro-ethanone |...)
Affinity DataIC50:  53nMAssay Description:Inhibition of recombinant Anopheles gambiae wild type AChE after 10 mins by Ellman assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Anopheles gambiae)
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50281126(1-(3-tert-Butyl-phenyl)-2,2,2-trifluoro-ethanone |...)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant Anopheles gambiae wild type AChE after 60 mins by Ellman assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50281126(1-(3-tert-Butyl-phenyl)-2,2,2-trifluoro-ethanone |...)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant human AChE after 10 mins by Ellman assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50281126(1-(3-tert-Butyl-phenyl)-2,2,2-trifluoro-ethanone |...)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant human AChE after 60 mins by Ellman assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed